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Over the previous two decades, rhetoricians came to grips with the transition of genetics to genomics by employing rigorous analyses of public discourse, analysis characterized by respect for diverse audiences, attention to precisely what is said, and the historicity of texts. In so doing, they provided helpful models for addressing a new wave of genomics that may threaten to change “genomic medicine” from the curing of disease into the remaking of human beings and the earth’s biosphere. Their work can be read as supporting and illustrating an integrative model of biological and discursive codes as opposed to the hierarchization of mind over body, or the reverse. The inauguration of Rhetoric of Health & Medicine creates a valuable locus for building upon such work, ready to address the new wave of genomics and the on-going challenge of being social creatures who remake ourselves and others.